Cells converts Pyruvate to CO2 collectively
Hence the Kreb cycle.
Kreb cycle connects glycolysis with the electron transport chain.
Pyruvate enters the cycle in the form of Acetyl CoA
1 complete cycle produces 1 molecule FADH and 1 NADH
which then both donate an electron pair each.
Acetyl CoA combines with oxaloacetic acid
To create a citric acid. That's how it begins.
Then a water removed and added makes it isocitric acid,
Which, in turn, oxidized and loses CO2.
Then alpha-ketoglutaric is oxidized again,
Losing carbon dioxide with an NADH spin.
Then through a phosphorylation
Succinyl CoA congeals a GDP to GTP to toss back CoASH.
CHORUS:
Acetyl CoA, citric acid, iso-,
Alpha-ketoglutaric, succinyl CoA,
Succeeded by succinic, fumaric and malic,
Then oxaloacetic starts the cycle again.
Soon we see succinic acid forming a fumaric acid
As it forms an FADH2 along the way.
Water washed upon fumaric makes it into acid malic.
Now there's only one step left, so let's be on our way.
With one more oxidation, resisting degradation,
A final NADH is made and brings us to the end.
Oxaloacetic acid, first and last, a simple acid
Then accepts an acetyl CoA and starts again.
CHORUS
Hence the Kreb cycle.
Kreb cycle connects glycolysis with the electron transport chain.
Pyruvate enters the cycle in the form of Acetyl CoA
1 complete cycle produces 1 molecule FADH and 1 NADH
which then both donate an electron pair each.
Acetyl CoA combines with oxaloacetic acid
To create a citric acid. That's how it begins.
Then a water removed and added makes it isocitric acid,
Which, in turn, oxidized and loses CO2.
Then alpha-ketoglutaric is oxidized again,
Losing carbon dioxide with an NADH spin.
Then through a phosphorylation
Succinyl CoA congeals a GDP to GTP to toss back CoASH.
CHORUS:
Acetyl CoA, citric acid, iso-,
Alpha-ketoglutaric, succinyl CoA,
Succeeded by succinic, fumaric and malic,
Then oxaloacetic starts the cycle again.
Soon we see succinic acid forming a fumaric acid
As it forms an FADH2 along the way.
Water washed upon fumaric makes it into acid malic.
Now there's only one step left, so let's be on our way.
With one more oxidation, resisting degradation,
A final NADH is made and brings us to the end.
Oxaloacetic acid, first and last, a simple acid
Then accepts an acetyl CoA and starts again.
CHORUS